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Improving the diagnostic accuracy in parkinsonism: a three-pronged approach

Identifieur interne : 000037 ( Main/Exploration ); précédent : 000036; suivant : 000038

Improving the diagnostic accuracy in parkinsonism: a three-pronged approach

Auteurs : Marjolein B. Aerts [Pays-Bas] ; Rianne A J. Esselink [Pays-Bas] ; Bart Post [Pays-Bas] ; Bart P C. Van De Warrenburg [Pays-Bas] ; Bastiaan R. Bloem [Pays-Bas]

Source :

RBID : ISTEX:212CB70EA14FF890F29466744632AAF31EC4DF53

Abstract

Separating Parkinson's disease from the various causes of atypical parkinsonism (AP) is a common and clinically relevant challenge in clinical practice. Distinguishing between the different causes of AP is even more difficult. Here the authors discuss a systematic, clinically based and three-pronged approach that can assist clinicians in establishing the correct diagnosis in the consulting room. The three consecutive steps include: (1) to verify that the clinical syndrome truly represents parkinsonism (hypokinetic–rigid syndrome); (2) to search systematically for ‘red flags’ (alarm signs that may signal the presence of AP); and (3) to integrate these two steps, as a basis for a narrow differential diagnosis and a guide for further ancillary tests.

Url:
DOI: 10.1136/practneurol-2011-000132


Affiliations:


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<div type="abstract">Separating Parkinson's disease from the various causes of atypical parkinsonism (AP) is a common and clinically relevant challenge in clinical practice. Distinguishing between the different causes of AP is even more difficult. Here the authors discuss a systematic, clinically based and three-pronged approach that can assist clinicians in establishing the correct diagnosis in the consulting room. The three consecutive steps include: (1) to verify that the clinical syndrome truly represents parkinsonism (hypokinetic–rigid syndrome); (2) to search systematically for ‘red flags’ (alarm signs that may signal the presence of AP); and (3) to integrate these two steps, as a basis for a narrow differential diagnosis and a guide for further ancillary tests.</div>
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